Electrically triggered release
Conductive hydrogel microneedles paired neural recording with electrically triggered drug release in a mouse seizure model.
Qu et al. · Science Advances · 2024Menu
Programmable hydrogel.
A refillable port. A confined, responsive hydrogel. A controlled path for local release.
Published research
Soft neural interfaces
An injectable conductive hydrogel supported stable electrical coupling for vagus nerve stimulation in rats.
Yang et al. · Nature Communications · 2024Refillable access
Subcutaneous nanofluidic implants sustained drug delivery after refilling through the skin in rats and nonhuman primates.
Di Trani et al. · Advanced Therapeutics · 2022Local CNS delivery
Five adults received ventricular valproate infusion in an uncontrolled study; seizures fell, but pump failures required replacement.
Cook et al. · EClinicalMedicine · 2020Next: bench validation of refill, containment and triggered release.
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